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KMID : 0861420100140020055
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Korean Journal of Nuclear Medicine Technology
2010 Volume.14 No. 2 p.55 ~ p.59
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Evaluation of the Effective Methods for Renal Washout on 18F-FDG PET/CT
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Kim Seong-Su
Kim Jong-Cheol
Shin Yong-Cheol
Lee Sun-Do
Lee Nam-Ju
Kim Seung-Soo
Lee Chun-Ho
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Abstract
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Purpose: Renal excretion is the main route of FDG clearance in FDG PET/CT scan. Applying optimal method of renal excretion is very important for enhancing image quality and diagnostic accuracy. We evaluated several methods of renal excretion in FDG PET/CT scan.
Materials and Methods: Thirty patients with normal renal function were prospectively included. Patients were divided into three group and undergone early and delayed FDG PET/CT scans. (1) Delay group; at 1 hour later of early scan, delayed scan was performed without additional hydration, (2) Hydration group; at 1 hour later of early scan, delayed scan was performed with additional oral hydration (700 mL of water), (3) Lasix group; lasix was administered at the end of early scan and dealyed scan was performed 30 min later. Early and delayed scans were compared to evaluate efficiency of renal excretion. Visual and quantitative analyses were performed by experienced physician and technologist of
nuclear medicine.
Results: On the visual analysis, renal excretion was the most evident in Lasix group followed by Hydration group. Delay group showed poor renal excretion. On the quantitative analysis, washout rates were 9.2±20.7 %, 28.1±22.8 % and 29.5±23.1 % for Delay, Hydration and Lasix groups, respectively.
Conclusion: Administration of lasix was the best method for enhancing renal excretion. Delayed scan with hydration was also efficient method, but delayed scan without hydration was not adequate method.
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KEYWORD
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FDG-PET/CT , Renal excretion , Washout , Lasix
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